Torphy, Theodore J: search on Z-Library

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1

Characterization of two human cAMP-specific phosphodiesterase subtypes expressed in baculovirus-infected insect cells.

Bernard Y. Amegadzie, Charles R. Hanning, Megan M. McLaughlin, Miriam Burman, Lenora B. Cieslinski, George P. Livi, Theodore J. Torphy

Journal:

Cell Biology International

Year:

1995

File:

PDF, 410 KB

1995

2

Monoclonal antibodies: boundless potential, daunting challenges

Theodore J. Torphy

Journal:

Current Opinion in Biotechnology

Year:

2002

Language:

english

File:

PDF, 34 KB

english, 2002

3

Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response

Don E. Griswold, Edward F. Webb, John Breton, John R. White, Paul J. Marshall, Theodore J. Torphy

Journal:

Year:

1993

Language:

english

File:

PDF, 705 KB

english, 1993

4

Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B

Carol D Manning, Miriam Burman, Siegfried B Christensen, Lenora B Cieslinski, David M Essayan, Marilyn Grous, Theodore J Torphy, Mary S Barnette

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 155 KB

english, 1999

5

Identification, Characterization, and Functional Role of Phosphodiesterase Type IV in Cerebral Vessels

Willette, Robert N., Shiloh, Aaron O., Sauermelch, Charles F., Sulpizio, Anthony, Michell, Marcus P., Cieslinski, Lenora B., Torphy, Theodore J., Ohlstein, E. H.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1997

Language:

english

File:

PDF, 858 KB

english, 1997

6

Ovarian effects of SK&F 86002-A2 in the rat: Site of action

Richard F. Walker, Lester W. Schwartz, Theodore J. Torphy, John F. Newton, Jeanne M. Manson

Journal:

Toxicology and Applied Pharmacology

Year:

1988

Language:

english

File:

PDF, 4.48 MB

english, 1988

7

Open partnering of integrated drug discovery: continuing evolution of the pharmaceutical model

Steven Hutchins, Theodore Torphy, Christophe Muller

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

8

Critical Role of Conserved Histidine Pairs HNXXH and HDXXH in Recombinant Human Phosphodiesterase 4A

George A. Omburo, Susanne Jacobitz, Theodore J. Torphy, Robert W. Colman

Journal:

Cellular Signalling

Year:

1998

Language:

english

File:

PDF, 259 KB

english, 1998

9

What's in the Pipeline? Prospects for Monoclonal Antibodies (mAbs) as Therapies for Lung Diseases

Li Li, Anuk M Das, Theodore J Torphy, Don E Griswold

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 184 KB

english, 2002

10

Association between leukotriene B4-induced phospholipase D activation and degranulation of human neutrophils

Zhou Han-Liang, Marie Chabot-Fletcher, James J. Foley, Henry M. Sarau, Maritsa N. Tzimas, James D. Winkler, Theodore J. Torphy

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.22 MB

english, 1993

11

Association of the anti-inflammatory activity of phosphodiesterase 4 (PDE4) inhibitors with either inhibition of PDE4 catalytic activity or competition for [3H]rolipram binding

Mary S. Bamette, Joan O'Leary Bartus, Miriam Burman, Siegfried B. Christensen, Lenora B. Cieslinski, Klaus M. Esser, Uma S. Prabhakar, Julia A. Rush, Theodore J. Torphy

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 949 KB

english, 1996

12

Differential relaxant effects of isoproterenol on methacholine- versus leukotriene D4-induced contraction in the guinea-pig trachea

Theodore J. Torphy

Journal:

European Journal of Pharmacology

Year:

1984

Language:

english

File:

PDF, 367 KB

english, 1984

13

Differences in the ability of salbutamol to prevent and reverse LTC4-induced contractions of the guinea-pig isolated trachea: Influence of l-serine borate

Douglas W.P. Hay, Roseanna M. Muccitelli, Karen A. Wilson, Martin A. Wasserman, Theodore J. Torphy

Journal:

European Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 398 KB

english, 1986

14

Phosphodiesterases: the journey towards therapeutics

Theodore J Torphy, Clive Page

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 66 KB

english, 2000

15

Cysteinyl leukotrienes in asthma: old mediators up to new tricks

Douglas W.P. Hay, Theodore J. Torphy, Bradley J. Undem

Journal:

Trends in Pharmacological Sciences

Year:

1995

Language:

english

File:

PDF, 835 KB

english, 1995

16

Re-classification of NSAIDs: PGHS-2 selectivity is not a sufficient criterion to predict the safety efficacy of NSAIDs

Don E. Griswold, Robert R. Ruffolo, George Poste, Theodore J. Torphy

Journal:

Trends in Pharmacological Sciences

Year:

1997

Language:

english

File:

PDF, 133 KB

english, 1997

17

Monoclonal antibodies as a strategy for pulmonary diseases

Theodore J Torphy, Li Li, Don E Griswold

Journal:

Current Opinion in Pharmacology

Year:

2001

Language:

english

File:

PDF, 65 KB

english, 2001

18

New therapies for pulmonary diseases: the leading edge of a new drug discovery paradigm

Theodore J. Torphy, Peter J. Barnes

Journal:

Current Opinion in Pharmacology

Year:

2001

Language:

english

File:

PDF, 30 KB

english, 2001

19

β-Adrenoceptors, cAMP and airway smooth muscle relaxation: challenges to the dogma

Theodore J. Torphy

Journal:

Trends in Pharmacological Sciences

Year:

1994

Language:

english

File:

PDF, 753 KB

english, 1994

20

Mechanisms of adaptive supersensitivity: correlation of guinea pig atrial supersensitivity with modifications in adenylyl cyclase activity

Marie I. Roberts, Jeffrey M. Stadel, Theodore J. Torphy, William W. Fleming, David A. Taylor

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 1.41 MB

english, 1997

21

The Effect of Leukotriene (LT) Antagonists on Antigen (Ag)-induced Contractions of Human Bronchus (HB) and Guinea Pig Trachea (GPT)

STEPHANIE S. TUCKER, ROSEANNA M. MUCCITELLI, DOUGLAS W. P. HAY, JOHN G. GLEASON, RALPH F. HALL, MARTIN A. WASSERMAN, THEODORE J. TORPHY

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 168 KB

english, 1988

22

Cyclic GMP-dependent protein kinase activation in canine tracheal smooth muscle by methacholine and sodium nitroprusside

Fiscus, Ronald R., Torphy, Theodore J., Mayer, Steven E.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1984

Language:

english

File:

PDF, 924 KB

english, 1984

23

WINTER IN EUROPE

Fiscus, Ronald R., Torphy, Theodore J., Mayer, Steven E.

Journal:

Year:

1946

Language:

english

File:

PDF, 388 KB

english, 1946

24

Highway speed radar for pavement and bridge deck evaluation

Fiscus, Ronald R., Torphy, Theodore J., Mayer, Steven E.

Journal:

NDT & E International

Year:

1994

Language:

english

File:

PDF, 153 KB

english, 1994

25

Supplement 10: Oxygen Radicals and Lung Injury || Phosphodiesterase IV Inhibitors as Therapy for Eosinophil-Induced Lung Injury in Asthma

Theodore J. Torphy, Mary S. Barnette, Douglas W. P. Hay and David C. Underwood

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 1.25 MB

english, 1994

26

Phosphodiesterase Isozymes

TORPHY, THEODORE J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

1998

Language:

english

File:

PDF, 235 KB

english, 1998

27

Inhibitors of CoA-independent transacylase block the movement of arachidonate into 1-ether-linked phospholipids of human neutrophils

Chilton, Floyd H., Fonteh, Alfred N., Sung, Chiu-Mei, Hickey, Deirdre M. B., Torphy, Theodore J., Mayer, Ruth J., Marshall, Lisa A., Heravi, Javid D., Winkler, James D.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.40 MB

english, 1995

28

Crystal structure, absolute configuration, and phosphodiesterase inhibitory activity of (+)-1-(4-bromobenzyl)-4-[(3-cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone

Baures, Paul W., Eggleston, Drake S., Erhard, Karl F., Cieslinski, Lenora B., Torphy, Theodore J., Christensen, Siegfried B.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 473 KB

english, 1993

29

Biochemical Regulation of Airway Smooth Muscle Tone: Current Knowledge and Therapeutic Implications

Torphy, Theodore J.

Journal:

Journal of Basic and Clinical Physiology and Pharmacology

Year:

1987

Language:

english

File:

PDF, 3.81 MB

english, 1987

30

Considerations for the Conduct of Clinical Trials with Anti-inflammatory Agents in Cystic Fibrosis: A Cystic Fibrosis Foundation Workshop Report

Torphy, Theodore J, Allen, Janet, Cantin, André M., Konstan, Michael W., Accurso, Frank J., Joseloff, Elizabeth, Ratjen, Felix A, Chmiel, James F.

Journal:

Annals of the American Thoracic Society

Year:

2015

Language:

english

File:

PDF, 865 KB

english, 2015

31

Tumor Necrosis Factor- α –Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth-Muscle Cells

Ammit, Alaina J., Hoffman, Rebecca K., Amrani, Yassine, Lazaar, Aili L., Hay, Douglas W. P., Torphy, Theodore J., Penn, Raymond B., Panettieri, Reynold A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2000

Language:

english

File:

PDF, 382 KB

english, 2000

32

Inactivation of Recombinant Monocyte cAMP-Specific Phosphodiesterase by cAMP Analog, 8-[(4-Bromo-2,3-Dioxobutyl)thio]Adenosine 3â²,5â²-Cyclic Monophosphate

Omburo, George A., Torphy, Theodore J., Scott, Gilbert, Jacobitz, Susanne, Colman, Roberta F., Colman, Robert W.

Journal:

Year:

1997

File:

PDF, 228 KB

1997

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